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clinmed/2003030005v1 (April 1, 2003)
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A “didactic” Familial Combined Hyperlipoproteinemia case report with a early total occlusion of the right carotid.

Arrigo FG Cicero, Simona Nascetti, Egidio Pedro, Sergio D'Addato, and Antonio Gaddi

We report about a Caucasic patient, 51 years old, BMI= 25.95, affected by Familial Combined Hyperlipoproteinemia (FCH). The eco-colour Doppler exam shows a 100% occlusion of the right carotid (the patient is totally asymptomatic because of a perfect compensation of the brain circulation). Considering the blood pressure and plasma lipid levels found during a year when the patient was been totally untreated, and when he 46 year old, his coronary, cerebrovascular, and cardiovascular disease estimated risk varied respectively in a range of 9-24.10, 1.30-18, and 11.7-23.6; the relative risks varied respectively in a range of 0.10-5.35, 2.08-3.66, and 1.87-3.39; the biologic age varied in the range of 47-57, 44-50 and 45-52 years. Many FCH patients could be not adequately treated until the appearance of serious atherosclerosis complication as the early total occlusion of a carotid.





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